| Date | Opponent / Event | Location | Time / Result |
| Thu., Sep. 3 | at Utah  |
Salt Lake City, Utah | L, 24-17 |
| Sat., Sep. 12 | vs. Oregon State |
Michigan Stadium | 12:00 p.m. ET |
| Sat., Sep. 19 | vs. UNLV |
Michigan Stadium | 12:00 p.m. ET |
| Sat., Sep. 26 | vs. Brigham Young |
Michigan Stadium | TBA |
| Sat., Oct. 3 | at Maryland * |
College Park, Md. | 8:00 p.m. ET |
| Sat., Oct. 10 | vs. Northwestern – Homecoming * |
Michigan Stadium | 3:30 p.m. ET |
| Sat., Oct. 17 | vs. Michigan State * |
Michigan Stadium | TBA |
| Sat., Oct. 31 | at Minnesota * |
Minneapolis, Minn. | 7:00 p.m. CT |
| Sat., Nov. 7 | vs. Rutgers * |
Michigan Stadium | TBA |
| Sat., Nov. 14 | at Indiana * |
Bloomington, Ind. | TBA |
| Sat., Nov. 21 | at Penn State * |
State College, Pa. | TBA |
| Sat., Nov. 28 | vs. Ohio State * |
Michigan Stadium | TBA |
| Sat., Dec. 5 | Big Ten Championship Game |
Indianapolis, Ind. | TBA |
